BSPED2011

9 Nov 2011

16:00-17:30Main Meeting Registration
17:30-19:00Sanofi-Aventis Satellite Symposium
Satellite Symposium Programme (pdf)(1.18mb)”
19:00-19:45Welcome Reception
19:45-23:45Speakers Dinner by invitation only
Novo Nordisk

10 Nov 2011

08:50-09:00Welcome
Chair(s):Mehul Dattani
09:00-10:30Oral Communications 1
Chair(s):Helen Spoudea & Sabah Alvi
09:00OC1.1Surgical treatment of children with hyperparathyroidism: single centre experience
09:11OC1.2Isolation and characterisation of tumorigenic progenitors/stem cells with a stabilizing mutation in beta-catenin, in a mouse model of human adamantinomatous craniopharyngioma.
09:22OC1.3High likelihood of malignancy in patients presenting with a thyroid nodule
09:33OC1.4Growth Retardation and Severe Constipation due to the first human, dominant negative Thyroid Hormone Receptor Alpha mutation
09:44OC1.5DECONVOLUTION ANALYSIS OF 24H SERUM CORTISOL PROFILES INFORMS THE AMOUNT AND DISTRIBUTION OF HYDROCORTSIONE REPLACEMENT THERAPY
09:55OC1.6Twenty novel mutations in nicotinamide nucleotide transhydrogenase (NNT) causing FGD
10:06OC1.7Mild GH deficiency due to two novel homozygous mutations in the gene encoding Growth-Hormone Releasing Hormone receptor (GHRHR) in a single family
10:17OC1.8Mutations in PROKR2 but not PROK2 are associated with congenital hypopituitarism and septo-optic dysplasia
10:30-11:00Coffee
11:00-12:30Symposium 1 – Update on Adrenal Disorders
Chair(s):John Gregory
11:00S16Familial Glucocorticoid Deficiency: An Update
Adrian Clark (Queen Mary University of London, London, UK)
11:30S17Recent advances in our understanding of adrenal disease and development
John Achermann (London, United Kingdom)
12:00S18Health problems in Congenital Adrenal Hyperplasia – a UK perspective
Nils Krone (Sheffield, UK)
12:30-14:00Lunch
13:15-14:00Poster Tour
14:00-15:00Oral Communications 2 - Brief Communications
Chair(s):Wolfgang Hogler & Caroline Brain
14:00OC2.1Sperm cryopreservation in adolescent minors with cancer: factors predicting pre-treatment semen quality in 79 minors aged 12-18 years over 10 years
14:06OC2.2The assessment of bone microarchitecture by high resolution magnetic resonance imaging (micro MRI) in young adults with childhood onset disease
14:12OC2.3MCM4 mutation causes a novel DNA replication disorder associated with short stature and adrenal failure
14:18OC2.4Short Term Effects of Recombinant IGF-I therapy in children with Laron’s Syndrome.
14:24OC2.5A selective effect of IGFBP-3 on brain volumes in healthy children
14:30OC2.6What defines Vitamin D deficiency biochemically in children?
14:36OC2.7Selective reduction in trabecular bone mineral density during treatment for childhood acute lymphoblastic leukaemia
14:42OC2.8Novel SOX2 mutation: from clinical phenotype to identification of new molecular mechanisms of SOX2 action and interactions.
15:00-15:30Tea
15:30-16:30Symposium 2 – Pubertal Disorders
Chair(s):Mehul Dattani & Liz Crowne
15:30S19Novel insights into Hypogonadotrophic Hypogonadism
Nelly Pitteloud (Lausanne, Switzerland)
16:00S20Management of Delayed Puberty
Leo Dunkel (London, UK)
16:45-18:00BSPED Annual General Meeting
19:45-20:15Pre-dinner Welcome Reception
20:15-23:45Conference Dinner

11 Nov 2011

09:00-10:00Symposium 3 – Novel therapies/management in Diabetes Mellitus
Chair(s):Peter Hindmarsh & James Greening
09:00S21Insulin resistance syndromes
Robert Semple (University of Edinburgh, Edinburgh, UK)
09:30S22Use of insulin for the early treatment of Type 2 Diabetes Mellitus
Rury Holman ()
10:00-10:30BSPED Research Award winners presentation from 2010
Session head(s):Tim Cheetham
10:20-10:30BSPED Website Launch
Session head(s):Justin Davies
10:30-11:00Coffee
11:00-11:45Plenary Guest Lecture: Advances in our understanding of the Genetic Causes of Obesity
Session head(s):Sadaaf Farooqi
11:45-12:30Oral Communications 3 - Brief Communications
Chair(s):Tabitha Randell & Rakesh Amin
11:45OC3.1The impact of growth hormone deficiency (GHD) and growth hormone treatment (GHTx) on the cardiovascular risk in survivors of bone marrow transplantation with total body irradiation (BMT/TBI) in childhood
11:56OC3.2Clinical, genetic, histological and radiological heterogeneity of focal forms of congenital hyperinsulinism
12:07OC3.3Laparoscopic near total pancreatectomy for medically unresponsive diffuse congenital hyperinsulinism
12:18OC3.4The heterogeneity of hyperinsulinaemic hypoglycaemia in 19 patients with Beckwith-Wiedemann syndrome due to KvDMR1 hypomethylation.
12:30-13:30Lunch
13:30-14:15Oral Communications 4 - Brief Communications
Chair(s):Tabitha Randell & Rakesh Amin
13:30OC4.1Ethnicity Rather Than Deprivation Impacts on Diabetes Control and use of Treatment Regimen
13:41OC4.2White UK children are older, more obese and more insulin resistant than non-White UK children at diagnosis of type 2 diabetes: baseline results of the UK national Type 2 diabetes cohort.
13:52OC4.3Non-linear Dynamic Analysis of Glucose Regulation in Subjects with Type 2 Diabetes and Controls - Observed Variability and Liability (OVAL)
14:03OC4.4Natural history of background retinopathy in children and young people with diabetes
14:15-15:55Symposium 4 – Insulin Resistance and Type 2 Diabetes: Novel Insights
Chair(s):David Dunger & Jeremy Kirk
14:15S24Islet cell transplantation: an update
Peter Jones ()
14:45S25Immunology of Type 1 Diabetes Mellitus
Mark Peakman ()
15:15S26Update on closed loop systems for the treatment of Type 1 DM
Roman Havorka ()
15:55-16:00Close of Meeting