SFEBES2018

Monday 19 November 2018

09:00-17:00Registration
10:30-12:00Symposium 1: Curing Diabetes
Chair(s):Shareen Forbes (Edinburgh) & Ketan Dhatariya (Norwich)
Non-hormonal therapies
LOMOND AUDITORIUM
10:30S1.1Immunotherapy for type 1 diabetes
Colin Dayan (Cardiff, Wales)
11:00S1.2State of the art in islet cell therapy: preclinical advances in graft revascularization
Willem Staels (Brussels, Belgium)
11:30S1.3Very low calories and type 2 diabetes
Mike Lean (Glasgow, United Kingdom)
10:30-12:00Symposium 2: Big Data and Bone Disease
Chair(s):Paul Ardunel (Sheffield) & Jarod Sze Choong Wong (Glasgow)
Big Data and Bone
BOISDALE
10:30S2.1Osteoporosis Mega GWAS
Brent Richards (Montreal, Canada)
11:00S2.2Functional Genomics: New in vivo models of skeletal disease (Role of the IMPC)
Duncan Bassett (London)
11:30S2.3How rare bone disease will advance bone biology (Role of the Musculoskeletal GeCIP)
Kassim Javaid (Oxford, UK)
10:30-12:00Clinical Management Workshop 1: Aggressive Pituitary Tumours
Chair(s):Helen Simpson (London) & Claire Higham (Manchester)
Bringing out the big guns
ALSH
10:30CMW1.1How and when to use temozolamide in pituitary tumours
Ben Whitelaw (King's College Hospital NHS Foundation Trust, London, UK)
11:00CMW1.2When to intervene in recurring pituitary tumours
Caroline Hayhurst (Cardiff)
11:30CMW1.3Proton beam therapy-the future
Yen-Ch-ing Chang (London)
10:30-12:00Skills 1: Presentation skills
Chair(s):Caroline Gorvin (Birmingham) & Ruth Casey (Cambridge)
CARRON
10:30SK1.1How to write an Abstract
Paul Newey (University of Dundee, Dundee, United Kingdom)
10:50SK1.2Perfect Prize Posters
Francesca Spiga (Bristol)
11:05SK1.3How to give a 10 minute talk
Laura Matthews (Leeds)
11:25SK1.4How to write a paper
Maralyn Druce (Barts Health NHS Trust, London, UK)
11:45SK1.5How do I respond to peer review
Colin Farquharson (Edinburgh)
12:15-13:00Master Class 1: PCOS
LOMOND AUDITORIUM
12:15MC1.1Polycystic ovary syndrome; The role of androgen excess in disease pathogenesis and metabolic dysfunction
12:35MC1.2PCOS: Management
Stephen Franks (London)
12:15-13:00Meet the Expert 1: What the endocrinologist needs to know about genetics
ALSH
12:15MTE1.0What the endocrinologist needs to know about genetics
Marta Korbonits (London, UK)
12:15-13:00Meet the Expert 2: Glucocorticoids in metabolic health
BOISDALE
12:15MTE2.0Glucocorticoids in metabolic health
Onno Meijer (Leiden, The Netherlands)
12:15-13:00Skills 2: How do I pass the SCE
Chair(s):Amir Sam (London)
CARRON
12:15FSK1How do I pass the SCE
Graham Leese (Dundee, UK)
13:00-14:15LUNCH, EXHIBITION & POSTERS
HALL 1 & 2
14:15-14:45Plenary 1: SfE International Medal Lecture
Chair(s):Graham Williams (London)
LOMOND AUDITORIUM
14:15PL1Puberty: what are the neuroendocrine triggers for the biological end of childhood?
Ursula Kaiser (Boston, USA)
14:45-15:15Plenary 2: SfE Starling Medal Lecture
Chair(s):Barbara McGowan (London)
LOMOND AUDITORIUM
14:45PL2Hepatic fatty acid metabolism: the effect of metabolic and nutritional state
Leanne Hodson (Oxford)
15:30-17:00Symposium 3: Horizons in Adrenal Medicine
Chair(s):Mark Sherlock (Dublin, Ireland) & Earn Gan (Newcastle)
State of the adrenal - 2018
LOMOND AUDITORIUM
15:30S3.1Novel strategies in glucocorticoid replacement
Eystein Husebye (University of Bergen, Bergen, Norway)
16:00S3.2Steroid metabolomics in adrenal incidentaloma
Irina Bancos (Mayo Clinic, Minnesota, USA)
16:30S3.3What’s new in adrenal carcinoma
Gary Hammer (University of Michigan , Michigan, USA)
15:30-17:00Symposium 4: New treatments for bone disorders
Chair(s):S. Faisal Ahmed (Glasgow) & Chantal Chenu (London)
Bone Therapies
BOISDALE
15:30S4.1New treatment for common bone disease (Abaloparatide)
Felicia Cosman (New York, USA)
16:00S4.2New treatments for rare bone disease
Paul Arundel (Sheffield Children’s NHS Foundation Trust, Sheffield, UK)
16:30S4.3Rare bone disorders: New Genes, biology and therapeutic targets
Outi Makitie (Helsinki, Finland)
15:30-17:00Symposium 5: Breast Cancer
Chair(s):Evan Simpson (Edinburgh) & Chris McCabe (Birmingham)
Oestrogens and Beyond
CARRON
15:30S5.1Epigenetic modelling of the chromatin landscape in breast cancer
Luca Magnani (London)
16:00S5.2Metabolic pathways regulating breast cancer in obesity
Kristy A. Brown (New York, USA)
16:30S5.3Oncogenomic studies in hormone-associated cancers
Wilbert Zwart (Netherlands Cancer Insitute, Amsterdam, The Netherlands)
15:30-17:00Oral Communications 1: Translational Highlights
Chair(s):Carla Moran (Cambridge) & Paul Newey (Dundee)
ALSH
15:30OC1.1Resilient reproductive, bone and adrenal function in Expedition Ice Maiden, the first all-female, unassisted Antarctic crossing.
Robert Gifford (University of Edinburgh, Edinburgh, UK)
15:45OC1.2Vitamin D Insufficiency and Elevated Vitamin D Metabolite Ratios (VMR) are Associated with Increased Risk of Injuries: Results from the British Army Lower Limb Injury Prevention (ALLIP) Study
Jonathan Tang (Norwich)
16:00OC1.3Novel insights into the genetic architecture of thyroid disease
Peter Taylor (Cardiff University, Cardiff, UK)
16:15OC1.4Whole Genome Sequence analysis establishes correct diagnosis for a syndromic form of hyperuricaemia
Mark Stevenson (Oxford)
16:30OC1.5In vivo and ex vivo metabolomics in succinate dehydrogenase deficient tumorigenesis.
Ruth Casey (Cambridge University Hospital NHS Foundation Trust, Cambridge, United Kingdom)
16:45OC1.6Germline CYP2W1*6 and CYP2B6*6 polymorphisms as predicting markers of sensitivity to mitotane treatment in advanced adrenocortical carcinoma: a multicentric ENSAT study.
Cristina Ronchi (University of Birmingham, Birmingham, United Kingdom)
17:00-17:30Tea & Coffee
HALL 1 & 2
17:30-18:00Plenary 3: SfE Medal Lecture
Chair(s):Karen Chapman (Edinburgh)
LOMOND AUDITORIUM
17:30PL3HPA activity: Don’t forget the dynamics
Stafford Lightman (Bristol)
18:00-18:30Plenary 4: SfE Transatlantic Medal Lecture
Chair(s):Simon Pearce (Newcastle)
LOMOND AUDITORIUM
18:00PL4Circadian Clock Genes and the Transcriptional Architecture of the Clock Mechanism
Joseph Takahashi (Dallas, USA)
18:30-19:15Debate: This house believes that the gut is the conductor of the endocrine orchestra
Chair(s):Jeremy Tomlinson (Oxford)
Brain vs Gut
LOMOND AUDITORIUM
18:30D1.1PRO: This house believes that the gut is the conductor of the endocrine orchestra
Carel Le Roux (Dublin, Ireland)
18:45D1.2CON: This house believes that the gut is the conductor of the endocrine orchestra
Giles Yeo (University of Cambridge, Cambridge, UK)
19:15-19:20City Welcome from Bailey Elaine Ballantyne (Deputy Lord Provost)
LOMOND AUDITORIUM
19:30-21:00Presidential Welcome Reception
HALL 1 & 2
19:45-21:00Early Careers Dinner & Quiz
ALSH

Tuesday 20 November 2018

07:30-19:00Registration
07:45-08:30RESEARCH INCUBATOR
Chair(s):Jeremy Turner (Norwich) & Caroline Gorvin (Birmingham)
Hosted by the Bone & Calcium Network
DOCHART
NW1.1Prospero - Clinical Trial of Management of PHPT
Bill Fraser (Norwich, UK)
NW1.2Network Member survey discussion
NW1.3Update on Network Activities
07:45-08:30RESEARCH INCUBATOR
Chair(s):Giles Yeo (Cambridge), Waljit Dhillo (London), Marta Korbonits (London), Craig Beall (Exeter), Andrew Childs (London), Stephen Franks (London), Barbara McGowan (London) & Kevin Murphy (London)
Hosted by the Neuroendocrinology Network, Reproductive Endocrinology & Biology Network and the Metabolic & Obesity Network
CARRON
NW2.1Dynamic assessment of circadian biology by automated ambulatory microdialysis
Thomas Upton (University of Bristol, Bristol, UK)
NW2.2The uterine natural killer cell differentiation pathway
Rupsha Fraser (Edinburgh)
NW2.3Update on Network Activities
08:30-09:00Plenary 5: CET Visiting Professor Lecture
Chair(s):Stephen Ball (Manchester)
SIAD; a modern approach
LOMOND AUDITORIUM
08:30P5SIAD; a modern approach
Christopher Thompson (Dublin, Ireland)
09:00-10:00Early Careers Endocrinologists' Prize Lectures
Chair(s):Chris McCabe (Birmingham) & Wiebke Arlt (Birmingham)
LOMOND AUDITORIUM
09:00EC1.1Neurokinin 3 receptor antagonism – the magic bullet for hot flushes?
Julia Prague (Royal Devon and Exeter Hospital and University of Exeter Medical School, Devon and Exeter, UK)
09:30EC1.2The Importance of Local Sex Steroid Action in the Regulation of Fertility
Douglas Gibson (Edinburgh)
10:00-10:15Tea & Coffee
HALL 1 & 2
10:15-11:45Oral communications 2: Early Career 'Best of the Best'
Chair(s):Chris McCabe (Birmingham) & Wiebke Arlt (Birmingham)
ALSH
10:15OC2.124-hour adrenal steroid rhythms are readily detected by ULTRADIAN automated ambulatory microdialysis in man
Thomas Upton (University of Bristol, Bristol, UK)
10:30OC2.2Comparison of acute effects of corticosterone versus cortisol (hydrocortisone) infusion in adults with congenital adrenal hyperplasia
Catriona Kyle (Western General Hospital, Edinburgh, UK)
10:45OC2.3Prospective serum thyroid function and cognitive decline in the very old: the Newcastle 85+ study
Earn Gan (Newcastle upon Tyne)
11:00OC2.4Biochemical analysis of radioiodine uptake enhancement in endocrine cancer
Mohammed Alshahrani (Birmingham, United Kingdom)
11:15OC2.5Using integrative lipid systems biology to understand the role of Liver X receptors (LXRs) in male reproduction.
Sheba Jarvis (Imperial College London, London, UK)
11:30OC2.6Overexpression ofSKAP2in familial AIP mutation negativesomatotrophinomas
Hussain Al-Jabir (London)
10:15-11:45Clinical Management Workshop 2: Endocrine emergencies
Chair(s):Karin Bradley (Bristol) & Catherine Napier (Newcastle)
Too hot to handle?
LOMOND AUDITORIUM
10:15CMW2.1Adrenal crisis: prevention and management
Mark Sherlock (Royal College of Surgeons in Ireland, Dublin, Ireland)
10:45CMW2.2Phaechromocytoma crisis
Ruth Casey (Cambridge University Hospital NHS Foundation Trust, Cambridge, United Kingdom)
11:15CMW2.3Thyrotoxic crises
Carla Moran (Beacon Hospital and University College Dublin, Dublin, Ireland)
10:15-11:45Symposium 6: The most important nine months; impact of maternal health
Chair(s):Rebecca Reynolds (Edinburgh) & Robert Lindsay (Glasgow)
Long term consequences for the offspring
BOISDALE
10:15S6.1Impact of maternal cholestasis on health of the offspring
Catherine Williamson (Imperial College London, London, UK)
10:45S6.2Impact of maternal diabetes on child health
Susan Ozanne (Cambridge, UK)
11:15S6.3Biological mechanisms and environmental factors involved in brain programming by stressful early-life experiences
Aniko Korosi (Utrecht, The Netherlands)
10:15-11:45Nurse Session 1 - Pituitary adenomas - beyond surgery
Chair(s):Miriam Asia (Birmingham) & Louise Breen (London)
CARRON
10:15NS1.1Pre-treatment management of pituitary adenomas
Patsy Coskeran (London)
10:40NS1.2The role of gamma knife in the management of pituitary adenomas
John Newell-Price (University of Sheffield, Sheffield, UK)
11:05NS1.3Post-treatment management of the pituitary patient
Alison Milne (Aberdeen)
11:30NS1.4Patient experience of gamma knife
Philip Rouse (Bath)
12:00-12:45Meet the Expert 3: Biochemistry masterclass
Chair(s):Tricia Tan (London)
LOMOND AUDITORIUM
12:00MTE3.1Insulin assay
David Halsall (Cambridge)
12:15MTE3.2When and how to measure PTHrP and 1,25-D and FGF23
William Fraser (Norwich)
12:30MTE3.3IGF1 Assays
Gwen Wark (Guilford)
12:00-12:45Meet the Expert 4: Brown adipose tissue
CARRON
12:00MTE4Brown adipose tissue
Jan Nedergaard (Stockholm, Sweden)
12:00-12:45Meet the Expert 5: Non-surgical management of incurable thyroid cancer
DOCHART
12:00MTE5Non-surgical management of incurable thyroid cancer
Maria Alevizaki (Athens, Greece)
12:00-12:45Meet the Expert 6: Gender dysphoria
BOISDALE
12:00MTE6Gender dsyphoria
Leighton Seal (St George's Hospital, London, UK)
12:45-14:00LUNCH, EXHIBITION & POSTERS
HALL 1 & 2
13:00-14:00Industry sponsored satellite symposia
DOCHART
13:00-14:00Industry sponsored satellite symposia
ALSH
14:00-15:30Clinical Management Workshop 3: How do I...
Chair(s):Colin Perry (Glasgow) & Catriona Kyle (Edinburgh)
LOMOND AUDITORIUM
14:00CMW3.1How do I... Manage diarrhoea in patients with NETs
Mark Strachan (Edinburgh)
14:15CMW3.2How do I...obesity related hypogonadism
Daniel Cuthbertson (Liverpool)
14:30CMW3.3How do I...manage adults with CAH
Wiebke Arlt (MRC Laboratory of Medical Sciences, London, UK)
14:45CMW3.4How do I...short stature
Helena Gleeson (endocrinologist at Queen Elizabeth Hospital Birmingham, Birmingham, United Kingdom)
15:00CMW3.5How do I…access and manage osteoporosis in younger adults
Jarod Wong (Glasgow, UK)
15:15CMW3.6How do I...manage persistent acromegaly following primary treatment
Robert Murray (Leeds Teaching Hospitals NHS Trust, Leeds Teaching Hospitals NHS Trust, Leeds, UK)
14:00-15:30Oral communications 3 (Clinical): Obesity & Diabetes
Chair(s):Alison McNeilly (Dundee)
ALSH
14:00OC3.1Kisspeptin stimulates insulin secretion and modulates serum metabolites in humans
Chioma Izzi-Engbeaya (Imperial College London, London, UK)
14:15OC3.2Glucose regulates pancreatic β cell Ca2+ dynamics and connectivity in vivo in the anterior chamber of the mouse eye.
Victoria Salem (Imperial College London, London, UK)
14:30OC3.3Staging of non-alcoholic fatty liver disease through LC-MS/MS analysis of the urinary steroid metabolome
Ahmad Moolla (Oxford)
14:45OC3.4Knockout of Glucocorticoid Receptor on AgRP/NPY/GABA (ANG) Neurons Identifies a potential role for this neuronal population in mediating Glucocorticoid–induced Insulin Resistance in Female Mice
Erika Harno (Manchester)
15:00OC3.5Hypothalamic Arcuate Glucokinase and its Downstream Pathways are Critical in Glucose Homeostasis
Risheka Ratnasabapathy (London)
15:15OC3.65β-reductase (AKR1D1) is a potent regulator of hepatic insulin sensitivity, carbohydrate and lipid metabolism in vitroand in vivo
Nikolaos Nikolaou (Oxford, United Kingdom)
14:00-15:30Applied Physiology Workshop - GPCRs: hotspots and complexes
Chair(s):Marian Ludgate (Cardiff) & Rajesh Thakker (Oxford)
Old dogs with new tricks
BOISDALE
14:00APW1.1Calcium-sensing at 25 years
Caroline Gorvin (University of Birmingham, Birmingham, UK)
14:30APW1.2FSH and thermogenesis
Mone Zaidi (Mount Sinai Professor of Clinical Medicine, Director, Center for Translational Medicine and Pharmacology, Icahn Sinai School of Medicine at Mount Sinai, New York, USA)
15:00APW1.3The nanodomain organization of GPCR signalling: lessons from TSH receptors and beyond
Davide Calebiro (University of Birmingham, UK)
14:00-15:30Nurse Session 2 - Adrenal crisis & steroid education: raising the safety bar
Chair(s):Karen Campbell (Glasgow) & Christine Gibson (Manchester)
CARRON
14:00NS2.1The epidemiology of adrenal crisis
Anna Mitchell (Newcastle University, Newcastle, UK)
14:30NS2.2National Education Programme for Patients with Chronic Adrenal Insufficiency
Gesine Meyer (Frankfurt, Germany)
15:00NS2.3Adrenal crisis- not always the obvious and saving lives
Anne Marland (Oxford Centre for Diabetes, Endocrinology and Metabolism, Oxford, UK)
15:20NS2.4Adrenal crisis- not always the obvious - Case Study
Lisa Shepherd (University of Birmingham, Birmingham, UK)
15:30-16:00Tea & Coffee
HALL 1 & 2
16:00-17:30Oral communications 4: Clinical Highlights
Chair(s):Lisa Shepherd (Birmingham) & Chris Thompson (Dublin, Ireland)
LOMOND AUDITORIUM
16:00OC4.1Targeted molecular analysis in adrenocortical carcinomas: a strategy towards improved personalized prognostication
Cristina Ronchi (University of Birmingham, Birmingham, United Kingdom)
16:15OC4.2Kisspeptin- a novel clinical test of hypothalamic function in men with hypogonadotrophic hypogonadism
Pei Chia Eng (Imperial College London, London, UK)
16:30OC4.3A novel non-invasive Short Synacthen Test validated in healthy adult and paediatric populations
Charlotte Elder (Sheffield Children’s NHS Foundation Trust, Sheffield, UK)
16:45OC4.4An intravenous insulin protocol designed for pregnancy reduces neonatal hypoglycaemia after betamethasone administration in women with gestational diabetes.
Christopher Rowe (Newcastle, Australia)
17:00OC4.5Hypothalamic-Pituitary Adrenal axis recovery rate of patients with Glucocorticoid-Induced Adrenal Insufficiency (GC-induced AI)
Chona Feliciano (Birmingham)
17:15OC4.611C-Methionine PET/MRI is superior to MRI for localisation of functioning prolactinomas and may facilitate targeted intervention
Waiel Bashari (Cambridge)
16:00-17:30Clinical Management Workshop 4: Treating troublesome menopausal symptoms
Chair(s):Annice Mukherjee (Manchester) & Amir Sam (London)
Management of Menopause
BOISDALE
16:00CMW4.1HRT – efficacy and safety - who and for how long
Nick Panay (London, UK)
16:30CMW4.2Non-Hormonal Therapies for Climacteric Symptoms
Keith Spowart (Glasgow)
17:00CMW4.3Neurokinin B antagonism – novel therapy for menopausal flushing
Waljit Dhillo (London, UK)
16:00-17:30Symposium 7: The microbiome in endocrine disease
Chair(s):Jeremy Tomlinson (Oxford) & Aygul Dagbasi (London)
Bugs and hormones
ALSH
16:00S7.1The role of the gut microbiome in obesity
Johnathan Swann (London)
16:30S7.2The gut microbiota in ageing and inflammation
Gemma Walton (Reading)
17:00S7.3A role for the microbiome in autoimmune Graves' disease and orbitopathy
Marian Ludgate (Cardiff)
16:00-17:30Early Careers Endocrinologists: Navigating the Academic Pathway
Chair(s):Rowan Hardy (Birmingham) & Kate Lines (Oxford)
Routes through the maze
CARRON
16:00EC2.1The Scientific Fellowship Route
David Hodson (University of Oxford, Oxford, UK)
16:18EC2.2The Clinical Academic Route
Victoria Salem (Imperial College London, London, UK)
16:36EC2.3The route with a career break
Myriam Chimen (Birmingham)
16:54EC2.4The Lecturship Route
Matthew Simmonds (Lincoln)
17:12EC2.5What the funders are looking for
Lindsay Keir (London)
17:45-18:15Plenary 6: CET Lecture
Chair(s):Stephen Ball (Manchester)
Sex, steroids and development – clinical research from the NHS
LOMOND AUDITORIUM
17:45P6Sex, steroids and development – clinical research from the NHS
Gerard Conway (London)
18:15-19:00Society for Endocrinology AGM
LOMOND AUDITORIUM
19:00-21:00Conference Dinner
Drinks reception from 19:00hrs, seated by 20:00hrs
Glasgow Science Centre

Wednesday 21 November 2018

07:30-17:30Registration
07:45-08:30RESEARCH INCUBATOR
Chair(s):Jeremy Tomlinson (Oxford) & Scott MacKenzie (Glasgow)
Hosted by the Adrenal & Cardiovascular Network
DOCHART
NW3.1Guidelines for peri-operative steroid treatment in patients with adrenal insufficiency: Optimising management and future directions
NW3.2Update on Network Activities
07:45-08:30RESEARCH INCUBATOR
Chair(s):Rajesh Thakker (Oxford) & Paul Newey (Dundee)
Hosted by the Endocrine Neoplasia Syndromes Network
BOISDALE
NW4.1Clinical trial for pancreatic neuroendocrine tumours
Ben Challis (Cambidge) & Paul Newey)
NW4.2Establishing a UK RET research collaborative network
Tom Kurzawinski (University College London Hospitals NHS Foundation Trust, London, UK)
NW4.3Update on Network Activities
07:45-08:30RESEARCH INCUBATOR
Chair(s):Petros Perros (Newcastle-Upon-Tyne) & Carla Moran (Cambridge)
Hosted by the Thyroid Network
CARRON
NW5.1Agranulocytosis study
Bijay Vaidya (Exeter)
NW5.2Weight and thyrotoxicosis proposal
Angelos Kyriacou (Salford)
NW5.3Potential UK collaborative thyroid disease in pregnancy trail
Peter Taylor (Cardiff University, Cardiff, UK)
NW5.4Update on Network Activities
NW5.5New leads for Thyroid Network
08:30-09:00Plenary 7: British Thyroid Association Pitt-Rivers Lecture
Chair(s):Krishna Chatterjee (Cambridge)
LOMOND AUDITORIUM
P7How should we define optimal thyroid function?
Robin Peeters (Rotterdam, The Netherlands)
09:00-09:30Plenary 8: SfE Dale Medal Lecture
Chair(s):Graham Williams (London)
Disorders of Thyroid Hormone Action: insights into diverse biological processes
LOMOND AUDITORIUM
P8Disorders of Thyroid Hormone Action: insights into diverse biological processes
Krishna Chatterjee (Wellcome-MRC Institute of Metabolic Science, University of Cambridge, Cambridge, UK)
09:45-11:15Symposium 8: Thyroid in Pregnancy
Chair(s):Robin Peeters (Rotterdam, The Netherlands) & Bijay Vaidya (Exeter)
Thyroid trials throughout life what they mean for you
LOMOND AUDITORIUM
09:45S8.1TABLET TRIAL – implications for targeted levothyroxine in pregnancy
Kristien Boelaert (University of Birmingham, Birmingham, UK)
10:15S8.2CATS Obstetric and development – implications for thyroid screening in pregnancy
Peter Taylor (Cardiff University, Cardiff, UK)
10:45S8.3Iodine supplementation in pregnancy and effect on offspring neurodevelopment
Sarah Bath (Surrey)
09:45-11:15Senior Endocrinologists
Chair(s):Paul Belchetz (Leeds)
CARRON
09:45SE1.1Plasma Steroid Bioavailability: Hormone versus Metabolite
Geoffery Hammond (Vancouver, Canada)
10:15SE1.2Oestrogens: the good, the bad, and the unexpected
Evan Simpson (Edinburgh)
10:45SE1.3Why did the Queen die?
Ashley Grossman (Green Templeton College, University of Oxford, London, UK)
09:45-11:15Applied Physiology Workshop - Metabolites as hormones
Chair(s):Gareth Lavery (Birmingham) & Edward Chambers (London)
New hormones everywhere
ALSH
09:45APW2.1Metabolic and microbial investigation of weight loss surgery
Jia Li (London)
10:15APW2.2Short chain fatty acid signalling in human health and disease
Edward Chambers (London)
10:45APW2.3Gut metabolites and human health
Louis Cohen (New York, USA)
09:45-11:15Symposium 9: Induction and preservation of gonadal function
Chair(s):Marie Freel (Glasgow) & Julia Prague (London)
Start it, save it
BOISDALE
09:45S9.1How do I differentiate hypog hypog from constitutional delay
Nicola Bridges (London)
10:15S9.2Induction of spermatogenesis
Richard Quinton (Imperial College London, London, UK)
10:45S9.3Preservation of fertility
Melanie Davies (University College London, London, UK)
11:15-11:45Tea & Coffee
HALL 1 & 2
11:45-12:30Meet the Expert 7 - Thyroid Masterclass
Chair(s):Anna Mitchell (Newcastle Upon Tyne)
LOMOND AUDITORIUM
11:45MTE7.1Central Hypothyroidism - Diagnostic Vignettes
Nadia Schoenmakers (Cambridge Neuroscience, Cambridge, United Kingdom)
12:05MTE7.2Grey cases in Thyroidology
Petros Perros (Newcastle, United Kingdom)
11:45-12:30Meet the Expert 8 - Circulating tumour cells in NETs
Circulating tumour cells in NETs
BOISDALE
11:45MTE8Circulating tumour cells in NETs
Tim Meyer (London)
11:45-12:30Meet the Expert 9 - Pituitary ion channel activity in health and disease
Pituitary ion channel activity in health and disease
CARRON
11:45MTE9Pituitary ion channel activity in health and disease
Mike Shipston (Edinburgh)
11:45-12:30Meet the Expert 10: Service Improvements
Chair(s):John Newell-Price (Sheffield)
ALSH
11:45MTE10Getting it right first time (GIRFT) in Endocrinology
John Wass (Nuffield Health Oxford Hospital, Oxford, UK)
12:00MTE10The Society for Endocrinology peer review scheme
Antonia Brooke (Exeter)
12:15MTE10Optimising patient outcomes and time management: the perfect MDT
Helen Simpson (University College London Hospital, London, UK)
12:30-13:45LUNCH, EXHIBITION & POSTERS
HALL 1 & 2
13:45-15:15Oral Communications 5: Adrenal
Chair(s):Stafford Lightman (Bristol) & Sheba Jarvis (London)
BOISDALE
13:45OC5.1Timed urinary steroid profiling of patients with different degrees of cortisol excess: a proposal for a new test for the diagnosis of Cushing’s syndrome.
Alessandro Prete (Queen Elizabeth Hospital, Birmingham, UK)
14:00OC5.2Residual adrenal function in autoimmune Addison’s disease – effect of dual therapy with rituximab and depot tetracosactide
Catherine Napier (Newcastle upon Tyne Hospitals, Newcastle, UK)
14:15OC5.311βHSD1 mediates therapeutic glucocorticoid-induced muscle atrophy in chronic inflammatory disease.
Justine Webster (Birmingham)
14:30OC5.4Glucocorticoid receptor-mediated signalling inhibits mesenchymal cell proliferation via repression of the V1 isoform of versican during mouse lung development
Kelly Short (Melbourne, Australia)
14:45OC5.5Androgen modulation of mouse uterus: a tissue-based bioassay for testing endogenous and synthetic androgen receptor modulators (SARMs)
Ioannis Simitsidellis (Edinburgh)
15:00OC5.6Therapeutic glucocorticoids prevent local and systemic bone loss in the TNF-tg model of chronic inflammatory disease
Chloe Fenton (Birmingham)
13:45-15:15Clinical Management Workshop 5: How do I...
Chair(s):Nicola Zammitt (Edinburgh) & Kerri Devine (Newcastle)
LOMOND AUDITORIUM
13:45CMW5.1How do I...manage endocrinopathies in HIV patients
Alison Wren (London)
14:00CMW5.2How do I...manage Paget’s disease
Stephen Gallacher (Glasgow)
14:15CMW5.3How do I...manage thyroid eye disease
Petros Perros (Newcastle, United Kingdom)
14:30CMW5.4How do I...decide what drugs to stop to investigate primary aldosteronism
Marie Freel (Queen Elizabeth University Hospital, Glasgow, UK)
14:45CMW5.5How do I... which non-diabetic patients could benefit from a GLP-1 analogue
Barbara McGowan (Guys & St Thomas NHS Trust, London, UK)
15:00CMW5.6How do I...investigate sweating
Mark Strachan (Edinburgh)
13:45-15:15Symposium 10: Pancreatic NETs an update
Chair(s):Ruth Casey (Cambridge) & Mark Stevenson (London)
Challenges and opportunities in PNETs
CARRON
13:45S10.1Managing Pancreatic Neuroendocrine Tumours in MEN1
John Newell-Price (University of Sheffield, Sheffield, UK)
14:15S10.2Advances in EUS and endotherapy in PNETs
Stephen Pereira (London)
14:45S10.3Genetic Landscape of pancreatic neuroendocrine tumours
Chrissie Thirlwell (Exeter, UK)
13:45-15:15Oral Communications 6: Neuroendocrinology and Reproduction
Chair(s):Douglas Gibson (Edinburgh) & Christopher Thompson (Dublin)
ALSH
13:45OC6.1A controlled cross-sectional study of bone microarchitecture in transgender individuals
Jeffrey Zajac (Australia)
14:00OC6.2Towards an understanding of the function of the mineralocorticoid receptor in zebrafish: the stress response, behaviour and osmoregulation
Jack Paveley (Sheffield)
14:15OC6.4Kisspeptin receptor activity in human granulosa lutein cells
Lisa Owens (St James Hospital, Dublin, Ireland)
14:30OC6.5Is the metabolic phenotype altered in decidualised stromal cells from women with endometriosis?
Frances Collins (Edinburgh)
14:45OC6.6An epigenetic modifier reduces proliferation in pituitary cells and suppresses calcium-sensing receptor signalling.
Kate Lines (Oxford, United Kingdom)
15:00OC6.3Gamma Knife Radiosurgery for the primary management of Acromegaly
John Newell-Price (University of Sheffield, Sheffield, UK)
15:30-16:00Plenary 9: SfE European Medal Lecture
Chair(s):Eleanor Davies (Glasgow)
Molecular mechanisms in primary aldosteronism
LOMOND AUDITORIUM
P9Molecular mechanisms in primary aldosteronism
Maria-Christina Zennaro (Université Paris Cité, Paris , France)
16:00-16:30Plenary 10: SfE Jubilee Lecture
Chair(s):Karen Chapman (Edinburgh)
Ups and Downs of Nuclear Receptor Action
LOMOND AUDITORIUM
16:00P10Ups and Downs of Nuclear Receptor Action
Malcom Parker (London)
16:30-17:00Awards Ceremony
LOMOND AUDITORIUM
17:00-17:15Closing Remarks
LOMOND AUDITORIUM