SFEBES2019

    09:00 - 21:00 
    REGISTRATION
    10:30 - 10:35 
    WELCOME
    10:35 - 11:05 
    What Is New
    10:35

    Session starts at 10:35
    WIN1
    What is New in Basic Endocrinology Research
    Caroline Gorvin (Birmingham, UK)

    10:50

    Session starts at 10:35
    WIN2
    What is New in Clinical Endocrinology Research
    John Newell-Price (Sheffield UK)

    11:10 - 12:40 
    How do I…1
    11:10

    Session starts at 11:10
    Management of osteoporosis in adolescence and young adults

    11:25

    Session starts at 11:10
    How do I manage an incidental finding of a thyroid nodule
    Kristien Boelaert (Birmingham, UK)

    11:40

    Session starts at 11:10
    How do I decide which patients with gynaecomastia need more detailed evaluation
    Sarah Ali (London, UK)

    11:55

    Session starts at 11:10
    How do I manage hair loss and hair growth in PCOS
    Aled Rees (Cardiff, UK)

    12:10

    Session starts at 11:10
    How do I induce spermatogenesis

    12:25

    Session starts at 11:10
    How do I choose between drug treatments for medical weight management
    Lucinda Summers (Salford, UK)

    11:10 - 12:40 
    Clinical Management Workshop 1: Salt & Water
    Don’t be hung out ‘too’ dry
    11:10

    Session starts at 11:10
    Management of hyponatraemia
    Steve Ball (Manchester, UK)

    11:40

    Session starts at 11:10
    Diabetes Insipidus- management challenges and pitfalls
    Mark Hannon (Bantry, Ireland)

    12:10

    Session starts at 11:10
    Co-peptin- a new player in the diagnosis of salt and water balance
    Mirjam Christ-Crain (Basal, Switzerland)

    11:10 - 12:40 
    Basic Physiology Workshop: Modelling endocrinology in vitro, in vivo & in silico
    11:10

    Session starts at 11:10
    In vivo models of endocrinology: new zebrafish models
    Francesco Argenton (Padua, Italy)

    11:40

    Session starts at 11:10
    In vitro models of endocrinology: organoids from pituitary and endometrium
    Hugo Vankelecom (Leuven, Belgium)

    12:10

    Session starts at 11:10
    In silico models of endocrinology: mathematical modelling of endocrine systems
    Margaritis Voliotis (Exeter, UK)

    12:40 - 13:55 
    LUNCH, EXHIBITION, SATELLITES & POSTERS
    14:00 - 14:30 
    Plenary 1:Clinical Endocrinology Trust Lecture
    14:00

    Session starts at 14:00
    Controlling cortisol in cardiometabolic disease
    Brian Walker (Newcastle-Upon-Tyne, UK)

    14:30 - 15:00 
    Plenary 2: Society for Endocrinology Starling Medal Lecture
    14:30

    Session starts at 14:30
    From its origins to the modern metabolic network
    Markus Ralser (London, UK)

    15:05 - 16:35 
    Oral Communications 1 - Metabolism and Obesity
    15:05

    Session starts at 15:05
    OC1.1
    Intracrine activation of 11-oxygenated androgens by AKR1C3 modulates lipid metabolism in human female adipose tissue
    Lina Schiffer (Birmingham, United Kingdom)

    15:20

    Session starts at 15:05
    OC1.2
    Hepatic de novo lipogenesis is suppressed and fat oxidation is increased by omega-3 fatty acids at the expense of glucose metabolism
    Leanne Hodson (Oxford, United Kingdom)

    15:35

    Session starts at 15:05
    OC1.3
    Metabolic and functional effects of fatty acid overload on in vitro tissue engineered skeletal muscle.
    Mark Turner (Loughborough, United Kingdom)

    15:50

    Session starts at 15:05
    OC1.4
    5β-reductase (AKR1D1) is downregulated in patients with non-alcoholic fatty liver disease and protects against hepatocellular carcinoma cell proliferation in vitro.
    Nikolaos Nikolaou (Oxford, United Kingdom)

    16:05

    Session starts at 15:05
    OC1.5
    Prolyl-hydroxylase 3 maintains β-cell glucose-sensing under metabolic stress
    Federica Cuozzo (Birmingham, United Kingdom)

    16:20

    Session starts at 15:05
    OC1.6
    Metabolic surgery reduces kidney SGLT2 expression in mice
    Elina Akalestou (London, United Kingdom)

    15:05 - 16:35 
    Oral Communications 2 - Neuroendocrinology, Pituitary and Neoplasia
    15:05

    Session starts at 15:05
    OC2.1
    Differential effects of subcutaneous pulsatile versus oral hydrocortisone replacement therapy on fMRI resting state and task based emotional processing in Patients with Primary Adrenal insufficiency
    Georgina Russell (Bristol, United Kingdom)

    15:20

    Session starts at 15:05
    OC2.2
    Investigating the role of AIP in pituitary tumourigenesis
    Anisha Mistry (London, United Kingdom)

    15:35

    Session starts at 15:05
    OC2.3
    ErbB receptor signalling in MCF7 breast cancer cells: an information theoretic approach
    Robert J. P. Pope (Bristol, United Kingdom)

    15:50

    Session starts at 15:05
    OC2.4
    Investigating the role of vagal Y2R in PYY3-36-mediated appetite suppression
    Aldara Martin Alonso (London, United Kingdom)

    16:05

    Session starts at 15:05
    OC2.5
    Efnb2 controls pituitary gland development by regulating proliferation of the pituitary stem/progenitor cells and EMT within the pituitary stem cell niche.
    Angelica Gualtieri (London, United Kingdom)

    16:20

    Session starts at 15:05
    OC2.6
    Post-operative copeptin analysis as a predictor of diabetes insipidus after pituitary surgery
    Hussam Rostom (Oxford, United Kingdom)

    15:05 - 16:35 
    Oral Communications 3 - Bone and Calcium
    15:05

    Session starts at 15:05
    OC3.1
    A mouse model generated by CRISPR-Cas9 with a frameshift mutation in the nuclear factor 1/X (NFIX) gene has phenotypic features reported in Marshall-Smith Syndrome (MSS) patients
    Kreepa Kooblall (Oxford, United Kingdom)

    15:20

    Session starts at 15:05
    OC3.2
    Hypophosphatasia in adulthood - are patients really “unaffected”
    Zhuo Min Chong (Glasgow, United Kingdom)

    15:35

    Session starts at 15:05
    OC3.3
    Generation of a long acting parathyroid hormone hybrid analogue through fusion to a binding protein
    Lina Sorour (Sheffield, United Kingdom)

    15:50

    Session starts at 15:05
    OC3.4
    Characterisation of rare GNA11 variants reveals 8 novel residues important for signalling by the calcium-sensing receptor: Relevance for FHH and ADH
    Anna Gluck (Oxford, United Kingdom)

    16:05

    Session starts at 15:05
    OC3.5
    Mutational analysis of a patient with familial hypocalciuric hypercalcaemia identifies a novel p.Ser182Cys mutation, which is predicted to disrupt the calcium sensing receptor (CaSR) extracellular domain
    Ultan Healy (Oxford, United Kingdom)

    16:20

    Session starts at 15:05
    OC3.6
    The role of biased calcium-sensing receptor signalling in urinary calcium excretion and kidney stone disease
    Michelle Goldsworthy (Oxford, United Kingdom)

    16:35 - 17:05 
    TEA & COFFEE
    17:05 - 18:05 
    Innovation Session 1: Advances in understanding skeletal disease
    17:05

    Session starts at 17:05
    Identifying new skeletal disease
    Mäkitie Outi (Helsinki Finland)

    17:25

    Session starts at 17:05
    Hyponatramia and osteoporosis
    Joesph G. Verbalis (Washington, USA)

    17:45

    Session starts at 17:05
    Bone fragility in patients with chronic kidney diseases
    Martine Cohen-Solal (Paris, France)

    17:05 - 18:05 
    Innovation Session 2: Big data in space and time
    17:05

    Session starts at 17:05
    Single cell RNA-seq of endocrine organs
    Karine Rizzoti (London, UK)

    17:35

    Session starts at 17:05
    Data Science Approaches to GPCRs and Nuclear Receptors
    M. Madan Babu ((Cambridge, UK))

    17:05 - 18:05 
    Innovation Session 3: NIHR Pathways to clinical impact
    17:05

    Session starts at 17:05
    From basic science to life changing therapies
    Waljit Dhillo (London, UK)

    17:25

    Session starts at 17:05
    Health Care Professionals, Industry and the NHS: delivering innovation
    John Wilding (Liverpool, UK)

    17:45

    Session starts at 17:05
    Championing Rare Disease Research
    Marta Korbonits (London, UK)

    18:10 - 18:40 
    Plenary 3: Society for Endocrinology Dale Medal Lecture
    18:10

    Session starts at 18:10
    From Carney complex to gigantism and Cushing disease: an insight in the genetics of pituitary tumors
    Constantine Stratakis (Rockville, USA)

    18:40 - 19:10 
    Debate: Nature vs Nurture
    18:40

    Session starts at 18:40
    AGAINST - This house believes nature not nurture determines our bodyweight
    John Wilding (Liverpool, UK)

    18:40

    Session starts at 18:40
    FOR - This house believes nature not nurture determines our bodyweight
    Sadaf Farooqi (Cambridge, UK)